Aptamer Screening Services

With extensive experience in aptamer development, our scientists are confident in providing a full range of aptamer screening services to advance science and technology development. Creative Biolabs is able to provide aptamer screening services in an efficient and high-quality manner.

SELEX technology can be used to obtain aptamers with specific binding ability to the target. Aptamers have been shown to partially replace antibodies in research and clinical applications, and are a promising technology area.

Schematic diagram of the SELEX processFig 1. Schematic diagram of the SELEX process [1].

The key to the development of aptamer technology is the screening of aptamers with high affinity and specificity for the target. Over the past decade, the aptamer screening technology has been improved to improve the efficiency and effectiveness of screening, and new methods such as ablation screening, compound target screening, genomic screening, capillary screening, etc. have been generated to promote the development of this technology.

Important advantages of aptamer over antibodyFig 2. Important advantages of aptamer over antibody [1].

Advantages of Aptamer

  • Short cycle time and high affinity and specificity of aptamer assays compared to monoclonal antibodies.
  • Compared to antibody assays, the aptamers obtained from screening are easy to synthesize in large quantities in vitro, reproducible, stable and easy to store.
  • Aptamer screening is simple and easy to perform, and the cost of the assay is low.
  • A wide range of aptamer targets, including pesticides, tissues, cells, viruses, proteins, toxins, vitamins and allergens.
  • Aptamers are easily labeled with fluorescence and their activity is not affected, so they can be easily combined with other assay technologies.

Applications of Aptamer

Similar to monoclonal antibodies, aptamers can specifically recognize and bind to their targets. Due to their simple preparation, ease of modification and stability, aptamers have been used in various fields of molecular biology, biotechnology and biomedicine.

Aptamers as Diagnostics
  • Pathogen identification
  • Cancer Marker Identification
  • Stem Cell Identification
  • Environmental pollution monitoring
    • Aptamer of heavy metal ions
    • Aptamers of pesticides
    • Aptamers for environmental toxins
    • Aptamers for pesticides
Biosensors
  • Aptamer-based biosensors are used to detect disease biomarkers, monitor environmental contaminants, or ensure food safety
Aptamer Therapeutics
  • Aptamers act as inhibitors of protein targets
  • Aptamer as a carrier for delivery of therapeutic agents to target cells or tissues

Our Services

With our technology platform, Creative Biolabs provides high-quality aptamer screening services.

We committed to help our customers obtain high-quality aptamers more efficiently. If you are interested in this service, please contact us for more details.

Advantages of Our Services

Creative Biolabs provides the most comprehensive services for aptamer development projects. Our cutting-edge technology allows our researchers to fulfill your requirement from various aspects and to offer the most suitable solution for your project.

  • Excellent researchers in the field of aptamer screening
  • Efficient and high-quality service at the most competitive price
  • Providing high-quality, high affinity aptamers
  • Shortest lead time for the success of your project

Service Process

Service Process

Reference

  1. Sun H, et al. A highlight of recent advances in aptamer technology and its application[J]. Molecules, 2015, 20(7): 11959-11980.
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